MARY MALLON: Late 30s/early 40s. Mezzo/Belter. The infamous Typhoid Mary. Boisterous and brazen, yet kind-hearted. Hard-working and devoutly Catholic. An Irish-born American who lives and works in New York as a hired chef. She’s publicly known as an asymptomatic carrier of Typhoid and has previously been arrested and quarantined on North Brother Island. 

MARGARET: 20s/30s. Alto/Mezzo. Brooklyn native. As Mary’s co-worker at the hospital kitchen, Margaret goes around delivering meals to the patients. She has been working at the hospital for years now. She is overly nice and a bit of a gossip — she’s seen it all and would be happy to tell you about it. Just like everyone in New York, she’s read all the headlines about Typhoid Mary. She’s lost family members to typhoid.

GEORGE SOPER: 30s/40s. Baritone. Big mustache. A sanitation engineer who had worked for the New York City Department of Health. He spends his time trying to discover the causes of urban diseases as a sort of public health private investigator. Eight years earlier, he tracked down and identified Mary as the cause of a Long Island typhoid outbreak, which led to her first quarantine. He has now been tasked with discovering the cause of a typhoid outbreak at Sloane Hospital for Women. A clinical man with a nervous disposition. He is not eager to arrest Mary for a second time but knows it is his duty.

A POLICE OFFICER: 30s/40s. A silent, imposing figure of the law. He is accompanying Soper on his investigation of the hospital.